mouse models

Caenorhabditis elegans

specialized ribosomes

cellular senescence


Markus Schosserer is postdoc/lecturer at University of Natural Resources and Life Sciences, Vienna, Department of Biotechnology, Vienna, Austria since 2012. He received his PhD in Biotechnology from the same university in 2012.

His research interests lie in the areas of Biogerontology and RNA biology, with special emphasis on RNA modifications, ribosomes, cellular senescence and Caenorhabditis elegans. Markus Schosserer is also interested in advanced microscopy techniques, including Raman and STED. His teaching activities include courses on Biology of Aging, Animal Cell Culture, Microscopy and Flow Cytometry.

Markus Schosserer co-authored 22 papers (November 2018) and presented his work at several national in international conferences. He won four poster prizes, two best talk awards and collaborates actively with researchers in several other disciplines of ageing research and RNA/ribosome biology.


model systems:

mammalian cells

Caenorhabditis elegans

transgenic mice

RNA/ribosome biology:

bisulfite sequencing/COBRA

measurement of bulk protein synthesis by OPP incorporation

translational fidelity assays

ageing research:

lifespan (yeast, C. elegans, D. melanogaster, mice)

healthspan phenotyping of C. elegans (locomotion, electrophysiology of the pharynx, memory function, stress resistance)

healthspan phenotyping of mice (frailty index, memory function)

cellular senescence (serial passaging, SIPS), confirmation of senescent phenotype (SA-beta-Gal, BrdU-assay, morphology, SASP, apoptosis)


life cell imaging

Raman microspectroscopy

gSTED super-resolution microscopy


Schosserer, M; Minois, N; Angerer, TB; Amring, M; Dellago, H; Harreither, E; Calle-Perez, A; Pircher, A; Gerstl, MP; Pfeifenberger, S; Brandl, C; Mohr, T; Sonntagbauer, M; Kriegner, A; Linder, A; Weinhäusel, A; Steiger, M; Mattanovich, D; Rinnerthaler, M; Karl, T; Sharma, S; Entian, KD; Kos, M; Breitenbach, M; Wilson, IBH; Polacek, N; Grillari-Voglauer, R; Breitenbach-Koller, L; Grillari, J (2015): Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan. Nature Communications 2015; 6/6158


Nagelreiter, F; Coats, MT; Klanert, G; Gludovacz, E; Borth, N; Grillari, J; Schosserer, M (2018): OPP Labeling Enables Total Protein Synthesis Quantification in CHO Production Cell Lines at the Single-Cell Level. Biotechnol J. 2018; Apr;13(4):e1700492


Schosserer, M; Grillari, J; Breitenbach, M (2017): The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy. Front Oncol. 2017; 7:278


Schosserer, M; Banks, G; Dogan, S; Dungel, P; Fernandes, A; Presen, DM; Matheu, A; Osuchowski, M; Potter, P; Sanfeliu, C; Tuna, BG; Varela-Nieto, I; Bellantuono, I (2018): Modelling physical resilience in ageing mice. Mech Ageing Dev. 2018


Garschall, K; Dellago, H; Gáliková, M; Schosserer, M; Flatt, T; Grillari, J (2017): Ubiquitous overexpression of the DNA repair factor dPrp19 reduces DNA damage and extends Drosophila life span. npg Aging and Mechanisms of Disease 2017; 3(5)


Khan, A; Dellago, H; Terlecki-Zaniewicz, L; Karbiener, M; Weilner, S; Hildner, F; Steininger, V; Gabriel, C; Mück, C; Jansen-Dürr, P; Hacobian, A; Scheideler, M; Grillari-Voglauer, R; Schosserer, M; Grillari, J (2017): SNEV(hPrp19/hPso4) Regulates Adipogenesis of Human Adipose Stromal Cells. Stem Cell Reports 2017; 8(1):21-29