Know-How here

Key publications here

Post-transcriptional regulation of LINE-1 retrotransposition by AID/APOBEC and ADAR deaminases.

Orecchini E, Frassinelli L, Galardi S, Ciafrè SA, Michienzi A. Chromosome Res. 2018 Mar;26(1-2):45-59. doi: 10.1007/s10577-018-9572-5

 

Restricting retrotransposons: ADAR1 is another guardian of the human genome.

Orecchini E, Frassinelli L, Michienzi A. RNA Biol. 2017 Nov 2;14(11):1485-1491. doi: 10.1080/15476286.2017.1341033.

 

ADAR1 restricts LINE-1 retrotransposition.

Orecchini E, Doria M, Antonioni A, Galardi S, Ciafrè SA, Frassinelli L, Mancone C, Montaldo C, Tripodi M, Michienzi A.

Nucleic Acids Res. 2017 Jan 9;45(1):155-168. doi: 10.1093/nar/gkw834

 

The ADAR1 editing enzyme is encapsidated into HIV-1 virions.

Orecchini E, Federico M, Doria M, Arenaccio C, Giuliani E, Ciafrè SA, Michienzi A.

Virology. 2015 Nov;485:475-80. doi: 10.1016/j.virol.2015.07.027.

 

ADAR2 editing enzyme is a novel human immunodeficiency virus-1 proviral factor.

Doria M, Tomaselli S, Neri F, Ciafrè SA, Farace MG, Michienzi A, Gallo A.

J Gen Virol. 2011 May;92(Pt 5):1228-32. doi: 10.1099/vir.0.028043-0.

 

Editing of HIV-1 RNA by the double-stranded RNA deaminase ADAR1 stimulates viral infection.

Doria M, Neri F, Gallo A, Farace MG, Michienzi A.

Nucleic Acids Res. 2009 Sep;37(17):5848-58. doi: 10.1093/nar/gkp604.