KEYWORDS
RNA modification
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RNA metabolism
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Adenosine Deamination
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ADARs
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Education: University of Vienna, Austria studies of Biology
Post Doc: Carnegie Institution of Washington, Department of Embryology
Professional:
1993-2000: University of Vienna, Department of Cell Biology, University Assistant
2000-2015: University of Vienna, Department of Chromosome Biology, Max F. Perutz Laboratories, Associate Prof.
since 2015: Medical University of Vienna, Center of Anatomy and Cell Biology, Division of Cell- and Developmental Biology, Full Prof.
Cell Biology of the Nucleus,
RNA Biology
Transgenic mice
RNA modifications
- Jain, M., Mann, T.D., Stulic, M., Rao, S.P., Kirsch, A., Pullirsch, D., Strobl, X., Rath, C., Reissig, L., Moreth, K., et al. (2018). RNA editing of Filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure. EMBO J.
http://emboj.embopress.org/content/early/2018/08/06/embj.201694813.long
- Tajaddod, M., Tanzer, A., Licht, K., Wolfinger, M.T., Badelt, S., Huber, F., Pusch, O., Schopoff, S., Janisiw, M., Hofacker, I., et al. (2016). Transcriptome-wide effects of inverted SINEs on gene expression and their impact on RNA polymerase II activity. Genome Biol 17, 220.
PMID: 27782844
- Licht, K., Kapoor, U., Mayrhofer, E., and Jantsch, M.F. (2016). Adenosine to Inosine editing frequency controlled by splicing efficiency. Nucleic Acids Res 44, 6398-6408.
PMID: 27112566
- Barraud, P., Banerjee, S., Mohamed, W.I., Jantsch, M.F., and Allain, F.H. (2014). A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1. Proc Natl Acad Sci U S A 111, E1852-1861.
PMID: 24753571
*Mannion, N.M., Greenwood, S.M., Young, R., Cox, S., Brindle, J., Read, D., Nellaker, C., Vesely, C., Ponting, C.P., McLaughlin, P.J., et al. (2014). The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. Cell reports 9, 1482-1494.
PMID: 25456137
