RNA modification

RNA metabolism

Adenosine Deamination



Education: University of Vienna, Austria studies of Biology

Post Doc: Carnegie Institution of Washington, Department of Embryology


1993-2000: University of Vienna, Department of Cell Biology, University Assistant

2000-2015: University of Vienna, Department of Chromosome Biology, Max F. Perutz Laboratories, Associate Prof.

since 2015:  Medical University of Vienna, Center of Anatomy and Cell Biology, Division of Cell- and Developmental Biology, Full Prof.



Cell Biology of the Nucleus,

RNA Biology

Transgenic mice

RNA modifications

  • Tajaddod, M., Tanzer, A., Licht, K., Wolfinger, M.T., Badelt, S., Huber, F., Pusch, O., Schopoff, S., Janisiw, M., Hofacker, I., et al. (2016). Transcriptome-wide effects of inverted SINEs on gene expression and their impact on RNA polymerase II activity. Genome Biol 17, 220.
    PMID: 27782844

  • Licht, K., Kapoor, U., Mayrhofer, E., and Jantsch, M.F. (2016). Adenosine to Inosine editing frequency controlled by splicing efficiency. Nucleic Acids Res 44, 6398-6408.
    PMID: 27112566

  • Barraud, P., Banerjee, S., Mohamed, W.I., Jantsch, M.F., and Allain, F.H. (2014). A bimodular nuclear localization signal assembled via an extended double-stranded RNA-binding domain acts as an RNA-sensing signal for transportin 1. Proc Natl Acad Sci U S A 111, E1852-1861.
    PMID: 24753571

*Mannion, N.M., Greenwood, S.M., Young, R., Cox, S., Brindle, J., Read, D., Nellaker, C., Vesely, C., Ponting, C.P., McLaughlin, P.J., et al. (2014). The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. Cell reports 9, 1482-1494.
PMID: 25456137