The goal of my PhD training was to find out novel signaling pathways affected by oxidative stress in two relevant pathophysiological conditions (cancer and vascular malformations). Then I shifted my research interest into the Stem Cell field by studying the transcriptional and epigenetic regulation of stem cell pluripotency and somatic cell reprogramming. Currently, my lab is interested in understanding epigenetic and epitranscriptomic regulation of transcription in the mammalian genome that governs cell fate decisions during embryonic development and human diseases. We aim to develop novel therapeutic strategies for age-related disorders (i.e. cancer) as well as rare diseases (i.e. multiple familial cerebral cavernomatosis). For this purpose, we use a variety of methods in molecular biology, genomic and proteomic approaches, genome editing and bioinformatics.