KEYWORDS

post-transcriptional regulation

RNA-binding proteins

regulatory networks

cancer


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BIO

My research interests are in the study of post-transcriptional regulatory networks, and their role in human health and tumorigenesis. I am particularly interested in deciphering the regulatory interplay of trans-factors such as RNA-binding proteins and non-coding RNAs by means of computational and molecular biology techniques.

KNOW-HOW
KEY PUBLICATIONS

Quattrone A and Dassi E. (2018) The architecture of the human RNA-binding protein regulatory network. bioRxiv. doi: 10.1101/041426.

Zuccotti P, Peroni D, Potrich V, Quattrone A, and Dassi E. (2018) An homeotic post-transcriptional network controlled by the RNA-binding protein RBMX. bioRxiv, doi:10.1101/400366 .

Dassi E, editor. (2016) Post-Transcriptional Gene Regulation: Methods and Protocols. Methods in Molecular Biology. Springer, doi: 10.1007/978-1-4939-3067-8.

Dassi E and Quattrone A. (2015) DynaMIT: the Dynamic Motif Integration Toolkit. Nucleic Acids Research, 10.1093/nar/gkv807.

Dassi E, Re A, Leo S, Tebaldi T, Pasini L, Peroni D and Quattrone A. (2014) AURA 2: Empowering discovery of post-transcriptional networks. Translation, 2(1): e27738.

Dassi E, Zuccotti P, Leo S, Provenzani A, Assfalg M, D’Onofrio M, Riva P, Quattrone A. (2013) Hyper conserved elements in vertebrate mRNA 3′-UTRs reveal a translational network of RNA-binding proteins controlled by HuR. Nucleic Acids Research, 41 (5): 3201-16.

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