KEYWORDS

RNA-binding proteins; MEX3A; SOX2; gastric cancer; colorectal cancer

BIO

BIO here

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KNOW-HOW

Know-How here

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KEY PUBLICATIONS

Key publications here

Bruun J, Sveen A, Barros R, Eide PW, Eilertsen I, Kolberg M, Pellinen T, David L, Svindland A, Kallioniemi O, Nesbakken A, Almeida R*, Lothe RA*. (2018) Prognostic, predictive and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer. Mol Oncol, In Press. *Shared last authorship.

Pereira B, Billaud M, Almeida R. (2017) RNA-Binding Proteins in Cancer: Old Players and New Actors. Trends in Cancer. 3:506-528.

Pinto R, Hansen L, Hintze J, Almeida R, Larsen S, Coskun M, Davidsen J, Mitchelmore C, David L, Troelsen JT, Bennett EP. (2017) Precise integration of inducible transcriptional elements (PrIITE) enables absolute control of gene expression. Nucleic Acids Res. 45(13):e123.

Camilo V, Garrido M, Valente P, Ricardo S, Amaral AL, Barros R, Chaves P, Carneiro F, David L, Almeida R. (2015) Differentiation reprogramming in gastric intestinal metaplasia and dysplasia: role of SOX2 and CDX2. Histopathology. 66:343-50.

Pereira B, Le Borgne M, Chartier NT, Billaud M, Almeida R. (2013) MEX-3 proteins: recent insights on novel post-transcriptional regulators. Trends Biochem Sci. 38:477-9. (Review)

Pereira B, Sousa S, Barros R, Carreto L, Oliveira P, Oliveira C, Chartier NT, Plateroti M, Rouault JP, Freund JN, Billaud M, Almeida R. (2013) CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness. Nucleic Acids Res. 41:3986-99.

Barros R, Freund JN, David L, Almeida R. (2012) Intestinal metaplasia revisited: function and regulation of CDX2. Trends Mol Med. 18:555-63. (Review)

Camilo V, Barros R, Sousa S, Magalhães AM, Lopes T, Santos AM, Pereira T, Figueiredo C, David L, Almeida R. (2012) Helicobacter pylori and the BMP pathway regulates CDX2 and SOX2 expression in gastric cells. Carcinogenesis. 33:1985-92.

Barros R, Costa LT, Pinto-de-Sousa J, Duluc I, Freund JN, David L, Almeida R. (2011) CDX2 autoregulation in human intestinal metaplasia of the stomach: impact on the stability of the phenotype. Gut. 60:290-8.

Barros R, Pereira B, Duluc I, Azevedo M, Mendes N, Camilo V, Jacobs RJ, Paulo P, Santos-Silva F, van Seuningen I, van den Brink GR, David L, Freund JN, Almeida R. (2008) Key elements of the BMP/SMAD pathway co-localize with CDX2 in intestinal metaplasia and regulate CDX2 expression in human gastric cell lines. J Pathol. 215:411-20.

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